BORA Polyclonal Antibody

Catalog number E-AB-53604-01

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Price for E-AB-53604-01

Size / count 20 µL

Specifications

Catalog number: E-AB-53604-01
Size / count: 20 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation, bipolar spindle assembly and chromosome segregation during mitosis. Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1. Bora is localized to the nucleus until mitosis is initiated, when it then translocates to the cytoplasm. This translocation is dependent on activated Cdc2, which releases Bora to bind and activate ARK-1 in the cytoplasm. Plk (polo-like kinase) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation on its N-terminus by ARK-1. It is through this mechanism that Bora and ARK-1 control cellular mitotic entry. Downregulation of the gene encoding Bora results in multipolar spindles in mitosis, a phenomenon that is also observed when ARK-1 function is blocked.
Abbreviation: BORA
UniProt: Q6PGQ7
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide of human BORA
Target: Aurora borealis; bora; bora; aurora kinase A activator; BORA; C13orf34; Chromosome 13 open reading frame 34 ; FLJ22624; HsBora; Protein aurora borealis; RP11-342J4.2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cell Biology; Signal transduction
Purification: Antigen affinity purification
Concentration: 1.8 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:50-1:300
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 61 kDa
Observed Molecular Weight: Refer to figures
Isotype: IgG

Frequently Asked Questions

What is the catalog number for BORA Polyclonal Antibody?

The catalog number for BORA Polyclonal Antibody is E-AB-53604.

What sizes are available for BORA Polyclonal Antibody?

BORA Polyclonal Antibody is available in the following size(s): 20 µL, 60 µL, 120 µL, 200 µL.

How many pack sizes does BORA Polyclonal Antibody come in?

BORA Polyclonal Antibody is available in 4 different pack sizes.

Is BORA Polyclonal Antibody in stock?

BORA Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BORA Polyclonal Antibody?

BORA Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BORA Polyclonal Antibody?

Estimated delivery time for BORA Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BORA Polyclonal Antibody?

The safety data sheet for BORA Polyclonal Antibody is available here: https://789.bio/eb/H44q50.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.