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Product details

ASC / TMS1 Polyclonal Antibody

Catalog number E-AB-60228-01

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Price for E-AB-60228-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-60228-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD) . The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
ASC / TMS1
UniProt
Q9ULZ3
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human ASC / TMS1 (NP_037390.2) .
Target
PYCARD; ASC; CARD5; TMS; TMS-1; TMS1; PYD and CARD domain containing; ASC / TMS1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Cell Biology
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
15kDa/19kDa/21kDa
Observed Molecular Weight
22kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S1567576923002242
Citation 02
https://www.nature.com/articles/s41598-022-04785-z
Citation 03
https://journals.lww.com/neuroreport/Fulltext/2021/06020/Protective_effects_of_melatonin_on_the_white.1.aspx?context=LatestArticles
Isotype
IgG

Frequently Asked Questions

What is the catalog number for ASC / TMS1 Polyclonal Antibody?

The catalog number for ASC / TMS1 Polyclonal Antibody is E-AB-60228.

What sizes are available for ASC / TMS1 Polyclonal Antibody?

ASC / TMS1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does ASC / TMS1 Polyclonal Antibody come in?

ASC / TMS1 Polyclonal Antibody is available in 3 different pack sizes.

Is ASC / TMS1 Polyclonal Antibody in stock?

ASC / TMS1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ASC / TMS1 Polyclonal Antibody?

ASC / TMS1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ASC / TMS1 Polyclonal Antibody?

Estimated delivery time for ASC / TMS1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ASC / TMS1 Polyclonal Antibody?

The safety data sheet for ASC / TMS1 Polyclonal Antibody is available here: https://789.bio/eb/uL8ev5.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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