NR1I3 Polyclonal Antibody — image 1 of 2

Product details

NR1I3 Polyclonal Antibody

Catalog number E-AB-60529-01

Choose a variant (3 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-60529-01

Size / count 60 µL

Specifications

Catalog number: E-AB-60529-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation: NR1I3
UniProt: Q14994
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant fusion protein of human NR1I3 (NP_001070948.1) .
Target: NR1I3; CAR; CAR1; NR1I3
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 30-40kDa
Observed Molecular Weight: 45kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for NR1I3 Polyclonal Antibody?

The catalog number for NR1I3 Polyclonal Antibody is E-AB-60529.

What sizes are available for NR1I3 Polyclonal Antibody?

NR1I3 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does NR1I3 Polyclonal Antibody come in?

NR1I3 Polyclonal Antibody is available in 3 different pack sizes.

Is NR1I3 Polyclonal Antibody in stock?

NR1I3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NR1I3 Polyclonal Antibody?

NR1I3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NR1I3 Polyclonal Antibody?

Estimated delivery time for NR1I3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NR1I3 Polyclonal Antibody?

The safety data sheet for NR1I3 Polyclonal Antibody is available here: https://789.bio/eb/yvvvLS.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.