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Product details

(KO Validated) DNMT1 Polyclonal Antibody

Catalog number E-AB-60994-01

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Price for E-AB-60994-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-60994-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Abbreviation
DNMT1
UniProt
P26358
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein of human DNMT1 (NP_001370.1) .
Target
ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
144kDa/183kDa/184kDa
Observed Molecular Weight
200kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for (KO Validated) DNMT1 Polyclonal Antibody?

The catalog number for (KO Validated) DNMT1 Polyclonal Antibody is E-AB-60994.

What sizes are available for (KO Validated) DNMT1 Polyclonal Antibody?

(KO Validated) DNMT1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does (KO Validated) DNMT1 Polyclonal Antibody come in?

(KO Validated) DNMT1 Polyclonal Antibody is available in 3 different pack sizes.

Is (KO Validated) DNMT1 Polyclonal Antibody in stock?

(KO Validated) DNMT1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures (KO Validated) DNMT1 Polyclonal Antibody?

(KO Validated) DNMT1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for (KO Validated) DNMT1 Polyclonal Antibody?

Estimated delivery time for (KO Validated) DNMT1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for (KO Validated) DNMT1 Polyclonal Antibody?

The safety data sheet for (KO Validated) DNMT1 Polyclonal Antibody is available here: https://789.bio/eb/LWjHOK.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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