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Product details

NPHP1 Polyclonal Antibody

Catalog number E-AB-61290-01

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Price for E-AB-61290-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-61290-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
NPHP1
UniProt
O15259
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human NPHP1 (NP_001121651.1) .
Target
NPHP1; JBTS4; NPH1; SLSN1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cell Biology; Signal transduction
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IF 1:50-1:100
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
69kDa/77kDa/83kDa
Observed Molecular Weight
83kDa
Citation 01
https://www.jbc.org/article/S0021-9258(17)49773-0/abstract
Isotype
IgG

Frequently Asked Questions

What is the catalog number for NPHP1 Polyclonal Antibody?

The catalog number for NPHP1 Polyclonal Antibody is E-AB-61290.

What sizes are available for NPHP1 Polyclonal Antibody?

NPHP1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does NPHP1 Polyclonal Antibody come in?

NPHP1 Polyclonal Antibody is available in 3 different pack sizes.

Is NPHP1 Polyclonal Antibody in stock?

NPHP1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NPHP1 Polyclonal Antibody?

NPHP1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NPHP1 Polyclonal Antibody?

Estimated delivery time for NPHP1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NPHP1 Polyclonal Antibody?

The safety data sheet for NPHP1 Polyclonal Antibody is available here: https://789.bio/eb/bD4Wb5.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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