(KO Validated) STAT3 Polyclonal Antibody — image 1 of 3

Product details

(KO Validated) STAT3 Polyclonal Antibody

Catalog number E-AB-62227-01

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Price for E-AB-62227-01

Size / count 60 µL

Specifications

Catalog number: E-AB-62227-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Abbreviation: STAT3
UniProt: P40763
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant fusion protein of human STAT3 (NP_644805.1) .
Target: ADMIO; ADMIO1; APRF; HIES; STAT3; Stat3
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Developmental Biology; Signal Transduction; Stem Cells
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 83kDa/87kDa/88kDa
Observed Molecular Weight: 90kDa
Citation 01: https://www.frontiersin.org/articles/10.3389/fendo.2018.00574/full
Isotype: IgG

Frequently Asked Questions

What is the catalog number for (KO Validated) STAT3 Polyclonal Antibody?

The catalog number for (KO Validated) STAT3 Polyclonal Antibody is E-AB-62227.

What sizes are available for (KO Validated) STAT3 Polyclonal Antibody?

(KO Validated) STAT3 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does (KO Validated) STAT3 Polyclonal Antibody come in?

(KO Validated) STAT3 Polyclonal Antibody is available in 3 different pack sizes.

Is (KO Validated) STAT3 Polyclonal Antibody in stock?

(KO Validated) STAT3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures (KO Validated) STAT3 Polyclonal Antibody?

(KO Validated) STAT3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for (KO Validated) STAT3 Polyclonal Antibody?

Estimated delivery time for (KO Validated) STAT3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for (KO Validated) STAT3 Polyclonal Antibody?

The safety data sheet for (KO Validated) STAT3 Polyclonal Antibody is available here: https://789.bio/eb/qLKy10.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.