Product details

AKT Polyclonal Antibody

Catalog number E-AB-63467-01

Choose a variant (3 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-63467-01

Size / count 60 µL

Specifications

Catalog number: E-AB-63467-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Abbreviation: AKT
UniProt: P31749
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: A synthetic peptide of human AKT (NP_005154.2) .
Target: AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA; AKT1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC; IF
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Signaling transduction
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: IHC 1:50-1:100; IF 1:50-1:100
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for AKT Polyclonal Antibody?

The catalog number for AKT Polyclonal Antibody is E-AB-63467.

What sizes are available for AKT Polyclonal Antibody?

AKT Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does AKT Polyclonal Antibody come in?

AKT Polyclonal Antibody is available in 3 different pack sizes.

Is AKT Polyclonal Antibody in stock?

AKT Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AKT Polyclonal Antibody?

AKT Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for AKT Polyclonal Antibody?

Estimated delivery time for AKT Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AKT Polyclonal Antibody?

The safety data sheet for AKT Polyclonal Antibody is available here: https://789.bio/eb/vnbPWP.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.