Caspase-3 Polyclonal Antibody — image 1 of 7

Product details

Caspase-3 Polyclonal Antibody

Catalog number E-AB-63510-01

Choose a variant (3 options)

Selecting a variant updates its price, size and availability.

Price for E-AB-63510-01

Size / count 60 µL

Specifications

Catalog number: E-AB-63510-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Abbreviation: Caspase-3
UniProt: P42574
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: A synthetic peptide of human Caspase-3 (NP_004337.2) .
Target: CPP32; CPP32B; SCA-1; Active Caspase 3; CASP3; active Caspase-3; Caspase 3; Caspase-3 p12; caspase-3
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC; IF
Field of Research: Cancer; Cell Biology; Metabolism; Neuroscience
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: IHC 1:50-1:200; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01: https://onlinelibrary.wiley.com/doi/abs/10.1111/and.14185
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Caspase-3 Polyclonal Antibody?

The catalog number for Caspase-3 Polyclonal Antibody is E-AB-63510.

What sizes are available for Caspase-3 Polyclonal Antibody?

Caspase-3 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does Caspase-3 Polyclonal Antibody come in?

Caspase-3 Polyclonal Antibody is available in 3 different pack sizes.

Is Caspase-3 Polyclonal Antibody in stock?

Caspase-3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caspase-3 Polyclonal Antibody?

Caspase-3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Caspase-3 Polyclonal Antibody?

Estimated delivery time for Caspase-3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caspase-3 Polyclonal Antibody?

The safety data sheet for Caspase-3 Polyclonal Antibody is available here: https://789.bio/eb/vjX9i9.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.