VEGFA Polyclonal Antibody

Catalog number E-AB-64001-01

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Price for E-AB-64001-01

Size / count 60 µL

Specifications

Catalog number: E-AB-64001-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
Abbreviation: VEGFA
UniProt: P15692
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: A synthetic peptide of human VEGFA (NP_001165094) .
Target: VEGFA; MVCD1; VEGF; VPF; L VEGFA; VEGF A
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Cancer; Cardiovascular; Metabolism; Developmental Biology; Signal Transduction
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IF 1:50-1:200
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 15-27kDa/34-45kDa
Observed Molecular Weight: 16kDa/35kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for VEGFA Polyclonal Antibody?

The catalog number for VEGFA Polyclonal Antibody is E-AB-64001.

What sizes are available for VEGFA Polyclonal Antibody?

VEGFA Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does VEGFA Polyclonal Antibody come in?

VEGFA Polyclonal Antibody is available in 3 different pack sizes.

Is VEGFA Polyclonal Antibody in stock?

VEGFA Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures VEGFA Polyclonal Antibody?

VEGFA Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for VEGFA Polyclonal Antibody?

Estimated delivery time for VEGFA Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for VEGFA Polyclonal Antibody?

The safety data sheet for VEGFA Polyclonal Antibody is available here: https://789.bio/eb/W9GWP4.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.