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Product details

PD-L1 Polyclonal Antibody

Catalog number E-AB-65810-01

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Price for E-AB-65810-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-65810-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
Abbreviation
PD-L1
UniProt
Q9NZQ7
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of human PD-L1 (NP_054862.1) .
Target
B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; CD274
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology
Purification
Affinity purification
Concentration
1mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for PD-L1 Polyclonal Antibody?

The catalog number for PD-L1 Polyclonal Antibody is E-AB-65810.

What sizes are available for PD-L1 Polyclonal Antibody?

PD-L1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does PD-L1 Polyclonal Antibody come in?

PD-L1 Polyclonal Antibody is available in 3 different pack sizes.

Is PD-L1 Polyclonal Antibody in stock?

PD-L1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD-L1 Polyclonal Antibody?

PD-L1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PD-L1 Polyclonal Antibody?

Estimated delivery time for PD-L1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD-L1 Polyclonal Antibody?

The safety data sheet for PD-L1 Polyclonal Antibody is available here: https://789.bio/eb/58CGCS.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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