Histone H2AX Polyclonal Antibody

Specifications

Catalog number

E-AB-67407-01

Size / count

60 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Abbreviation

Histone H2AX

UniProt

P16104

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human Histone H2AX.

Target

H2A.X; H2A/X; H2AX; Histone H2AX; H2AFX; histone H2AX; gamma H2A.X; γH2AX

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IF

Field of Research

Cancer; Epigenetics and Nuclear Signaling

Purification

Affinity purification

Concentration

1mg/mL

Dilution

IF 1:50-1:100

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG