Cox2 Polyclonal Antibody

Specifications

Catalog number

E-AB-68287-01

Size / count

60 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Abbreviation

Cox2

UniProt

P35354

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant fusion protein of human Cox2

Target

PTGS2; COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2; Cox2

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cardiovascular; Metabolism; Signal transduction

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

WB 1:1000-1:4000; IHC 1:50-1:200

Buffer

PBS with 0.05% proclin300,50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

68kDa

Observed Molecular Weight

69KDa

Isotype

IgG