CYCS Polyclonal Antibody

Specifications

Catalog number

E-AB-70033-01

Size / count

60 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

Abbreviation

CYCS

UniProt

P99999, P62898, P62897

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c

Target

Cytochrome C; Somatic; CYC; Cytochrome C; THC4; HCS.

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC; IF

Field of Research

Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction

Purification

Affinity purification

Concentration

1.5 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:500-1:1000; IF 1:200-1:800

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

12kDa

Observed Molecular Weight

12kDa

Citation 01

https://link.springer.com/article/10.1007/s11696-019-00894-8

Isotype

IgG