HMGB1 Polyclonal Antibody — image 1 of 4

Product details

HMGB1 Polyclonal Antibody

Catalog number E-AB-70044-01

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Price for E-AB-70044-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70044-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFB family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 both contain two DNA-binding domains, termed HMG boxes. HMG proteins bind single-stranded DNA but induce conformational changes in double-stranded DNA alone.
Abbreviation: HMGB1
UniProt: P09429, P63158, P63159
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse HMGB1
Target: Amphoterin; Chromosomal protein; nonhistone; HMG1; DKFZp686A04236; High mobility group 1; High mobility group box 1; High mobility group protein 1; High mobility group protein B1; high-mobility group (nonhistone chromosomal) protein 1; HMG-1; HMG1; HMG3; HMGB 1; HMGB1; HMGB1; NONHISTONE CHROMOSOMAL PROTEIN HMG1; SBP 1; Sulfoglucuronyl carbohydrate binding protein
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC; IF
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 1.45 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:200-1:800; IF 1:200-1:800
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 25kDa
Observed Molecular Weight: 25kDa
Citation 01: https://pubs.acs.org/doi/abs/10.1021/acsami.2c09462
Isotype: IgG

Frequently Asked Questions

What is the catalog number for HMGB1 Polyclonal Antibody?

The catalog number for HMGB1 Polyclonal Antibody is E-AB-70044.

What sizes are available for HMGB1 Polyclonal Antibody?

HMGB1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does HMGB1 Polyclonal Antibody come in?

HMGB1 Polyclonal Antibody is available in 3 different pack sizes.

Is HMGB1 Polyclonal Antibody in stock?

HMGB1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HMGB1 Polyclonal Antibody?

HMGB1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for HMGB1 Polyclonal Antibody?

Estimated delivery time for HMGB1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HMGB1 Polyclonal Antibody?

The safety data sheet for HMGB1 Polyclonal Antibody is available here: https://789.bio/eb/yLSSqT.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.