MMP9 Polyclonal Antibody

Specifications

Catalog number

E-AB-70060-01

Size / count

60 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Abbreviation

MMP9

UniProt

P14780

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein corresponding to Rat MMP9

Target

82 kDa matrix metalloproteinase-9;92 kDa gelatinase;92 kDa type IV collagenase; CLG 4B; CLG4B; Collagenase Type 4 beta; Collagenase type IV 92 KD; EC 3.4.24.35; Gelatinase 92 KD; Gelatinase B; Gelatinase beta; GelatinaseB; GELB; Macrophage gelatinase; MANDP2; Matrix metallopeptidase 9 (gelatinase B;92kDa gelatinase;92kDa type IV collagenase) ; Matrix Metalloproteinase 9; MMP 9; MMP-9; MMP9; MMP9; Type V collagenase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cell Biology; Cardiovascular; Signal Transduction

Purification

Affinity purification

Concentration

1 mg/mL

Dilution

IHC 1:200-1:500

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG