Product details

P27 Polyclonal Antibody

Catalog number E-AB-70069-01

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Price for E-AB-70069-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70069-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4) .
Abbreviation: P27
UniProt: P46527, P46414
Host: Rabbit
Reactivity: Human; Rat
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse P27 KIP1
Target: AA408329; AI843786; Cdki1b; CDKN 1B; CDKN 4; CDKN1B; CDKN4; CDN1B; Cyclin Dependent Kinase Inhibitor 1B; Cyclin dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor 1B (p27; Kip1) ; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; Cyclin-dependent kinase inhibitor p27 Kip1; KIP 1; KIP1; MEN1B; MEN4; OTTHUMP00000195098; OTTHUMP00000195099; p27; p27 Kip1; P27-like cyclin-dependent kinase inhibitor; p27Kip1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 0.89 mg/mL
Dilution: IHC 1:100-1:400
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01: https://www.nature.com/articles/s41598-022-11904-3
Citation 02: https://www.sciencedirect.com/science/article/pii/S0927776520305816
Citation 03: https://pubs.rsc.org/en/content/articlelanding/2020/ra/d0ra03467c
Isotype: IgG

Frequently Asked Questions

What is the catalog number for P27 Polyclonal Antibody?

The catalog number for P27 Polyclonal Antibody is E-AB-70069.

What sizes are available for P27 Polyclonal Antibody?

P27 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does P27 Polyclonal Antibody come in?

P27 Polyclonal Antibody is available in 3 different pack sizes.

Is P27 Polyclonal Antibody in stock?

P27 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P27 Polyclonal Antibody?

P27 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for P27 Polyclonal Antibody?

Estimated delivery time for P27 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P27 Polyclonal Antibody?

The safety data sheet for P27 Polyclonal Antibody is available here: https://789.bio/eb/fX5WnH.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.