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Product details

Vimentin Polyclonal Antibody

Catalog number E-AB-70081-01

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Price for E-AB-70081-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-70081-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Vimentin, also named as VIM, belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092), suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein,55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.
Abbreviation
Vimentin
UniProt
P08670, P20152, P31000
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse vimentin
Target
CTRCT30; Epididymis luminal protein 113; FLJ36605; HEL113; VIM; VIME; Vimentin
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Developmental Biology; Neuroscience; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1.1 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
57kDa
Observed Molecular Weight
57kDa
Citation 01
https://www.mdpi.com/2055064
Citation 02
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068511/
Citation 03
https://www.hindawi.com/journals/cjgh/2022/5332129/
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Vimentin Polyclonal Antibody?

The catalog number for Vimentin Polyclonal Antibody is E-AB-70081.

What sizes are available for Vimentin Polyclonal Antibody?

Vimentin Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does Vimentin Polyclonal Antibody come in?

Vimentin Polyclonal Antibody is available in 3 different pack sizes.

Is Vimentin Polyclonal Antibody in stock?

Vimentin Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Vimentin Polyclonal Antibody?

Vimentin Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Vimentin Polyclonal Antibody?

Estimated delivery time for Vimentin Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Vimentin Polyclonal Antibody?

The safety data sheet for Vimentin Polyclonal Antibody is available here: https://789.bio/eb/Cq10W9.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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