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Product details

BECN1 Polyclonal Antibody

Catalog number E-AB-70093-01

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Price for E-AB-70093-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-70093-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Abbreviation
BECN1
UniProt
Q14457, O88597, Q91XJ1
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Beclin1
Target
APG6; ATG 6; ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin 1 (coiled coil moesin like BCL2 interacting protein) ; Beclin 1 autophagy related; Beclin-1; Beclin1; BECN 1; Becn1; BECN1; Coiled coil myosin like BCL2 interacting protein; Coiled-coil myosin-like BCL2-interacting protein; GT197; Protein GT197; VPS 30; VPS30
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC; IF
Field of Research
Cancer; Epigenetics and Nuclear Signaling; Metabolism; Microbiology; Signal Transduction
Purification
Affinity purification
Concentration
2.6 mg/mL
Dilution
IHC 1:300-1:1000; IF 1:100-1:500
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for BECN1 Polyclonal Antibody?

The catalog number for BECN1 Polyclonal Antibody is E-AB-70093.

What sizes are available for BECN1 Polyclonal Antibody?

BECN1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does BECN1 Polyclonal Antibody come in?

BECN1 Polyclonal Antibody is available in 3 different pack sizes.

Is BECN1 Polyclonal Antibody in stock?

BECN1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BECN1 Polyclonal Antibody?

BECN1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for BECN1 Polyclonal Antibody?

Estimated delivery time for BECN1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BECN1 Polyclonal Antibody?

The safety data sheet for BECN1 Polyclonal Antibody is available here: https://789.bio/eb/Tur1yH.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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