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Product details

PDGFB Polyclonal Antibody

Catalog number E-AB-70120-01

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Price for E-AB-70120-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-70120-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Abbreviation
PDGFB
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse PDGFB
Target
Becaplermin; PDGF 2; PDGF B chain; PDGF subunit B; PDGF-2; PDGF2; Pdgfb; PDGFB; Platelet derived growth factor 2; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Platelet-derived growth factor subunit B; Proto-oncogene c-Sis; SIS; SSV
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC; IF
Field of Research
Cancer; Cardiovascular; Metabolism; Developmental Biology; Signal Transduction
Purification
Affinity purification
Concentration
410 μg/mL
Dilution
WB 1:500-1:2000; IHC 1:200-1:400
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
27kDa
Observed Molecular Weight
27kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for PDGFB Polyclonal Antibody?

The catalog number for PDGFB Polyclonal Antibody is E-AB-70120.

What sizes are available for PDGFB Polyclonal Antibody?

PDGFB Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does PDGFB Polyclonal Antibody come in?

PDGFB Polyclonal Antibody is available in 3 different pack sizes.

Is PDGFB Polyclonal Antibody in stock?

PDGFB Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PDGFB Polyclonal Antibody?

PDGFB Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PDGFB Polyclonal Antibody?

Estimated delivery time for PDGFB Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PDGFB Polyclonal Antibody?

The safety data sheet for PDGFB Polyclonal Antibody is available here: https://789.bio/eb/OeTar9.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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