Product details

ATF6 Polyclonal Antibody

Catalog number E-AB-70158-01

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Price for E-AB-70158-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70158-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.
Abbreviation: ATF6
UniProt: P18850, F6VAN0, G3V909
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ATF6
Target: Activating Transcription Factor 6; CAMP-Dependent Transcription Factor ATF-6 Alpha; Activating Transcription Factor 6 Alpha; Cyclic AMP-Dependent Transcription Factor ATF-6 Alpha; ATF6-Alpha; ACHM7; ATF6A.
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Affinity purification
Concentration: 1 mg/mL
Dilution: IHC 1:200-1:1000
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for ATF6 Polyclonal Antibody?

The catalog number for ATF6 Polyclonal Antibody is E-AB-70158.

What sizes are available for ATF6 Polyclonal Antibody?

ATF6 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does ATF6 Polyclonal Antibody come in?

ATF6 Polyclonal Antibody is available in 3 different pack sizes.

Is ATF6 Polyclonal Antibody in stock?

ATF6 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ATF6 Polyclonal Antibody?

ATF6 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for ATF6 Polyclonal Antibody?

Estimated delivery time for ATF6 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ATF6 Polyclonal Antibody?

The safety data sheet for ATF6 Polyclonal Antibody is available here: https://789.bio/eb/ernL0C.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.