Product details

FAS Monoclonal Antibody

Catalog number E-AB-70174-01

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Price for E-AB-70174-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70174-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: FAS, also named as CD95, APO-1, APT1, FAS1 and TNFRSF6, is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily, can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC) . FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro) . This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
Abbreviation: FAS
UniProt: P25445, P25446
Host: Mouse
Reactivity: Human; Mouse
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse FAS
Target: ALPS 1A; ALPS1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo-1 antigen; APO1; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen FAS; Apoptosis-mediating surface antigen FAS; APT 1; APT1; CD 95; CD 95 antigen; CD95; CD95 antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; Fas (TNF receptor superfamily; member 6) ; FAS 1; FAS 827dupA; Fas AMA; Fas; FAS Antigen; Fas cell surface death receptor; FAS1; FASLG receptor; FASTM; sFAS; Surface antigen APO1; TNF receptor superfamily; member 6; TNFRSF 6; TNFRSF6; TNR6; Tumor necrosis factor receptor superfamily member 6
Clonality: Monoclonal
Clone: 10E5B10
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Cell Biology; Immunology
Purification: Affinity purification
Concentration: 420 μg/mL
Dilution: IHC 1:200-1:800
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for FAS Monoclonal Antibody?

The catalog number for FAS Monoclonal Antibody is E-AB-70174.

What sizes are available for FAS Monoclonal Antibody?

FAS Monoclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does FAS Monoclonal Antibody come in?

FAS Monoclonal Antibody is available in 3 different pack sizes.

Is FAS Monoclonal Antibody in stock?

FAS Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FAS Monoclonal Antibody?

FAS Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for FAS Monoclonal Antibody?

Estimated delivery time for FAS Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FAS Monoclonal Antibody?

The safety data sheet for FAS Monoclonal Antibody is available here: https://789.bio/eb/LiPun9.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.