SIRT7 Polyclonal Antibody

Specifications

Catalog number

E-AB-70223-01

Size / count

60 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Abbreviation

SIRT7

UniProt

Q9NRC8, Q8BKJ9

Host

Rabbit

Reactivity

Human

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse SIRT7

Target

NAD dependent deacetylase sirtuin 7; NAD dependent protein deacetylase sirtuin 7; NAD-dependent protein deacetylase sirtuin-7; Regulatory protein SIR2 homolog 7; Silent mating type information regulation 2 homolog; Silent mating type information regulation 2 S.cerevisiae homolog 7; SIR2 L7; SIR2 like protein 7; Sir2 related protein type 7; SIR2; S.CEREVISIAE; HOMOLOG-LIKE 7; SIR2-like protein 7; SIR2L 7; SIR2L7; SIR7; SIRT 7; SIRT7; Sirtuin 7; Sirtuin type 7; Sirtuin7

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC

Field of Research

Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism

Purification

Affinity purification

Concentration

190 μg/mL

Dilution

IHC 1:200-1:400

Buffer

PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Isotype

IgG