IL10 Polyclonal Antibody

Catalog number E-AB-70235-01

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Price for E-AB-70235-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70235-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Interleukin (IL) -10 is an anti-inflammatory cytokine, produced by T helper (Th) cells, macrophages, monocytes, and B cells, that plays a crucial role in preventing inflammatory and autoimmune pathologies. It downregulates the expression of Th1 cytokines, MHC class II antigens, and co-stimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-κB activity, and is involved in the regulation of the JAK-STAT signaling pathway. IL-10, along with its receptors, describes an important role in pathogenesis of various diseases, including infectious, inflammatory, autoimmune diseases. IL-10 mutations are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
Abbreviation: IL10
UniProt: P18893 , P29456
Host: Rabbit
Reactivity: Mouse; Rat
Immunogen: KLH conjugated Synthetic peptide corresponding to IL-10
Target: CSIF; Cytokine synthesis inhibitory factor; GVHDS; IL 10; IL-10; IL10; IL10; IL10A; Interleukin 10; Interleukin-10; MGC126450; MGC126451; T-cell growth inhibitory factor; TGIF
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC; IF
Field of Research: Cancer; Immunology
Purification: Affinity purification
Concentration: 150 μg/mL
Dilution: IHC 1:200-1:1000; IF 1:200-1:1000
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01: https://www.hindawi.com/journals/omcl/2022/8244497/
Isotype: IgG

Frequently Asked Questions

What is the catalog number for IL10 Polyclonal Antibody?

The catalog number for IL10 Polyclonal Antibody is E-AB-70235.

What sizes are available for IL10 Polyclonal Antibody?

IL10 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does IL10 Polyclonal Antibody come in?

IL10 Polyclonal Antibody is available in 3 different pack sizes.

Is IL10 Polyclonal Antibody in stock?

IL10 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IL10 Polyclonal Antibody?

IL10 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for IL10 Polyclonal Antibody?

Estimated delivery time for IL10 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IL10 Polyclonal Antibody?

The safety data sheet for IL10 Polyclonal Antibody is available here: https://789.bio/eb/f58qb1.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.