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Product details

E-Cadherin Monoclonal Antibody

Catalog number E-AB-70249-01

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Price for E-AB-70249-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-70249-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Abbreviation
E-Cadherin
UniProt
P09803, Q9R0T4
Host
Mouse
Reactivity
Mouse; Rat
Immunogen
Recombinant protein corresponding to MouseE-cadherin
Target
Arc 1; CADH1; Cadherin 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD 324; CD324; CD324 antigen; cdh1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependant adhesion protein; LCAM; Liver cell adhesion molecule; UVO; Uvomorulin
Clonality
Monoclonal
Clone
EC125D
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Developmental Biology; Signal Transduction
Purification
Affinity purification
Concentration
1.6 mg/mL
Dilution
IHC 1:200-1:800
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Citation 01
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631930/
Isotype
IgG

Frequently Asked Questions

What is the catalog number for E-Cadherin Monoclonal Antibody?

The catalog number for E-Cadherin Monoclonal Antibody is E-AB-70249.

What sizes are available for E-Cadherin Monoclonal Antibody?

E-Cadherin Monoclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does E-Cadherin Monoclonal Antibody come in?

E-Cadherin Monoclonal Antibody is available in 3 different pack sizes.

Is E-Cadherin Monoclonal Antibody in stock?

E-Cadherin Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures E-Cadherin Monoclonal Antibody?

E-Cadherin Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for E-Cadherin Monoclonal Antibody?

Estimated delivery time for E-Cadherin Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for E-Cadherin Monoclonal Antibody?

The safety data sheet for E-Cadherin Monoclonal Antibody is available here: https://789.bio/eb/aTmnr5.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

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