Product details

PCNA Polyclonal Antibody

Catalog number E-AB-70285-01

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Price for E-AB-70285-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70285-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution; the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells.
Abbreviation: Proliferating Cell Nuclear Antigen
UniProt: Q12004, P17918, P04961
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant protein corresponding to Mouse PCNA
Target: ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNA; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Tags and Cell Markers
Purification: Affinity purification
Concentration: 470 μg/mL
Dilution: WB 1:500-1:2000; IHC 1:500-1:1000
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 36kDa
Observed Molecular Weight: 36kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for PCNA Polyclonal Antibody?

The catalog number for PCNA Polyclonal Antibody is E-AB-70285.

What sizes are available for PCNA Polyclonal Antibody?

PCNA Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does PCNA Polyclonal Antibody come in?

PCNA Polyclonal Antibody is available in 3 different pack sizes.

Is PCNA Polyclonal Antibody in stock?

PCNA Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PCNA Polyclonal Antibody?

PCNA Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for PCNA Polyclonal Antibody?

Estimated delivery time for PCNA Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PCNA Polyclonal Antibody?

The safety data sheet for PCNA Polyclonal Antibody is available here: https://789.bio/eb/L0yrrH.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.