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Product details

GDNF Polyclonal Antibody

Catalog number E-AB-70291-01

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Price for E-AB-70291-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-70291-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing.
Abbreviation
GDNF
UniProt
Q07731, P48540
Host
Rabbit
Reactivity
Mouse; Rat
Immunogen
KLH conjugated Synthetic peptide corresponding to mouse GDNF
Target
Astrocyte derived trophic factor; Astrocyte derived trophic factor 1; Astrocyte-derived trophic factor; ATF 1; ATF 2; Atf; ATF1; ATF2; gdnf; GDNF; Glial cell derived neurotrophic factor; Glial Cell Line Derived Neurotrophic Factor; Glial cell line-derived neurotrophic factor; Glial derived neurotrophic factor; HFB1 GDNF; hGDNF; HSCR3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Neuroscience; Developmental Biology
Purification
Affinity purification
Concentration
80 μg/mL
Dilution
IHC 1:100-1:500
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

Frequently Asked Questions

What is the catalog number for GDNF Polyclonal Antibody?

The catalog number for GDNF Polyclonal Antibody is E-AB-70291.

What sizes are available for GDNF Polyclonal Antibody?

GDNF Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does GDNF Polyclonal Antibody come in?

GDNF Polyclonal Antibody is available in 3 different pack sizes.

Is GDNF Polyclonal Antibody in stock?

GDNF Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GDNF Polyclonal Antibody?

GDNF Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for GDNF Polyclonal Antibody?

Estimated delivery time for GDNF Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GDNF Polyclonal Antibody?

The safety data sheet for GDNF Polyclonal Antibody is available here: https://789.bio/eb/nHWHK8.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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