CASP1 Polyclonal Antibody — image 1 of 3

Product details

CASP1 Polyclonal Antibody

Catalog number E-AB-70300-01

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Price for E-AB-70300-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70300-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Abbreviation: CASP1
UniProt: P29466, P29452, P43527
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant protein corresponding to Mouse Caspase1
Target: CASP-1; CASP1; CASP1; Caspase 1; Caspase-1 subunit p10; ICE; IL-1 beta-converting enzyme; IL-1BC; IL1 beta converting enzyme; IL1B convertase; Interleukin 1 beta convertase; Interleukin 1B converting enzyme; Interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Cell Biology; Metabolism
Purification: Affinity purification
Concentration: 1.2 mg/mL
Dilution: WB 1:500-1:2000; IHC 1:300-1:800
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 45kDa
Observed Molecular Weight: 45-47kDa,30kDa,35kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CASP1 Polyclonal Antibody?

The catalog number for CASP1 Polyclonal Antibody is E-AB-70300.

What sizes are available for CASP1 Polyclonal Antibody?

CASP1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does CASP1 Polyclonal Antibody come in?

CASP1 Polyclonal Antibody is available in 3 different pack sizes.

Is CASP1 Polyclonal Antibody in stock?

CASP1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CASP1 Polyclonal Antibody?

CASP1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CASP1 Polyclonal Antibody?

Estimated delivery time for CASP1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CASP1 Polyclonal Antibody?

The safety data sheet for CASP1 Polyclonal Antibody is available here: https://789.bio/eb/OinHGC.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.