COL1A1 Polyclonal Antibody — image 1 of 2

Product details

COL1A1 Polyclonal Antibody

Catalog number E-AB-70322-01

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Price for E-AB-70322-01

Size / count 60 µL

Specifications

Catalog number: E-AB-70322-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: COL1A1 (Collagen Type I Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL1A1 include Caffey Disease and Osteogenesis Imperfecta, Type I. Among its related pathways are Collagen chain trimerization and Transcription_Role of VDR in regulation of genes involved in osteoporosis. GO annotations related to this gene include identical protein binding and platelet-derived growth factor binding. An important paralog of this gene is COL2A1.This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Abbreviation: COL1A1
UniProt: P11087, P02452
Host: Rabbit
Reactivity: Mouse; Rat
Immunogen: Recombinant protein corresponding to Mouse COL1A1
Target: COL1A1; Alpha 1 type I collagen; Alpha-1 type I collagen; CO1A1; COL1A1; Collagen alpha-1 (I) chain; Collagen type I alpha 1; Procollagen type I C terminal propeptide
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Signal Transduction
Purification: Affinity purification
Concentration: 130 μg/mL
Dilution: IHC 1:300-1:1000
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for COL1A1 Polyclonal Antibody?

The catalog number for COL1A1 Polyclonal Antibody is E-AB-70322.

What sizes are available for COL1A1 Polyclonal Antibody?

COL1A1 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does COL1A1 Polyclonal Antibody come in?

COL1A1 Polyclonal Antibody is available in 3 different pack sizes.

Is COL1A1 Polyclonal Antibody in stock?

COL1A1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures COL1A1 Polyclonal Antibody?

COL1A1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for COL1A1 Polyclonal Antibody?

Estimated delivery time for COL1A1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for COL1A1 Polyclonal Antibody?

The safety data sheet for COL1A1 Polyclonal Antibody is available here: https://789.bio/eb/COOSmT.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.