Recombinant HMGB1 Monoclonal Antibody — image 1 of 2

Product details

Recombinant HMGB1 Monoclonal Antibody

Catalog number E-AB-81436-01

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Price for E-AB-81436-01

Size / count 50 µL

Specifications

Catalog number: E-AB-81436-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFB family, ATF-2 and c-Jun to activate transcription. Other studies indicate that phosphorylation of HMG protein is required to stimulate the transcriptional activity of the protein. Human HMG-1 and HMG-2 both contain two DNA-binding domains, termed HMG boxes. HMG proteins bind single-stranded DNA but induce conformational changes in double-stranded DNA alone.
Abbreviation: HMGB1
UniProt: P09429
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: A synthetic peptide of human HMGB1
Target: Amphoterin; Chromosomal protein; nonhistone; HMG1; DKFZp686A04236; High mobility group 1; High mobility group box 1; High mobility group protein 1; High mobility group protein B1; high-mobility group (nonhistone chromosomal) protein 1; HMG-1; HMG1; HMG3; HMGB 1; HMGB1; HMGB1; NONHISTONE CHROMOSOMAL PROTEIN HMG1; SBP 1; Sulfoglucuronyl carbohydrate binding protein
Clonality: Monoclonal
Clone: R07-2D8
Conjugation: Unconjugated
Applications: WB; IHC-P
Field of Research: Cancer; Epigenetics and Nuclear Signaling
Purification: Affinity Purified
Concentration: 300 μg/mL
Dilution: WB 1:1000-1:2000; IHC 1:50-1:100
Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 25kDa
Observed Molecular Weight: 25kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant HMGB1 Monoclonal Antibody?

The catalog number for Recombinant HMGB1 Monoclonal Antibody is E-AB-81436.

What sizes are available for Recombinant HMGB1 Monoclonal Antibody?

Recombinant HMGB1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant HMGB1 Monoclonal Antibody come in?

Recombinant HMGB1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant HMGB1 Monoclonal Antibody in stock?

Recombinant HMGB1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant HMGB1 Monoclonal Antibody?

Recombinant HMGB1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant HMGB1 Monoclonal Antibody?

Estimated delivery time for Recombinant HMGB1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant HMGB1 Monoclonal Antibody?

The safety data sheet for Recombinant HMGB1 Monoclonal Antibody is available here: https://789.bio/eb/rXXDaP.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.