Recombinant Caspase 3 Monoclonal Antibody — image 1 of 2

Product details

Recombinant Caspase 3 Monoclonal Antibody

Catalog number E-AB-81444-01

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Price for E-AB-81444-01

Size / count 50 µL

Specifications

Catalog number: E-AB-81444-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs MW of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3.
Abbreviation: Caspase 3
UniProt: P42574
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: A synthetic peptide of human Caspase 3
Target: A830040C14Rik; Apopain; CASP-3; CASP3; CASP3; Casp3a; Caspase 3; Caspase 3; apoptosis-related cysteine peptidase; Caspase 3; apoptosis-related cysteine protease; Caspase 3; apoptosis-related cysteine protease a; Caspase-3 subunit p12; CC3; CPP-32; CPP32; CPP32B; Cysteine protease CPP32; EC 3.4.22.56; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; Protein Yama; SCA 1; SCA-1; SREBP cleavage activity 1; Yama
Clonality: Monoclonal
Clone: R06-1B2
Conjugation: Unconjugated
Applications: WB; IHC-P
Field of Research: Cancer; Cell Biology; Metabolism; Neuroscience
Purification: Affinity Purified
Concentration: 300 μg/mL
Dilution: WB 1:500-1:1000; IHC 1:50-1:100
Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 32kDa
Observed Molecular Weight: 32kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant Caspase 3 Monoclonal Antibody?

The catalog number for Recombinant Caspase 3 Monoclonal Antibody is E-AB-81444.

What sizes are available for Recombinant Caspase 3 Monoclonal Antibody?

Recombinant Caspase 3 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Caspase 3 Monoclonal Antibody come in?

Recombinant Caspase 3 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Caspase 3 Monoclonal Antibody in stock?

Recombinant Caspase 3 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Caspase 3 Monoclonal Antibody?

Recombinant Caspase 3 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Caspase 3 Monoclonal Antibody?

Estimated delivery time for Recombinant Caspase 3 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Caspase 3 Monoclonal Antibody?

The safety data sheet for Recombinant Caspase 3 Monoclonal Antibody is available here: https://789.bio/eb/rDmDmT.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.