Recombinant Beclin 1 Monoclonal Antibody

Catalog number E-AB-81447-01

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Price for E-AB-81447-01

Size / count 50 µL

Specifications

Catalog number: E-AB-81447-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Abbreviation: Beclin 1
UniProt: Q14457
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant protein of human Beclin 1
Target: APG6; ATG 6; ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin 1 (coiled coil moesin like BCL2 interacting protein) ; Beclin 1 autophagy related; Beclin-1; Beclin1; BECN 1; Becn1; BECN1; Coiled coil myosin like BCL2 interacting protein; Coiled-coil myosin-like BCL2-interacting protein; GT197; Protein GT197; VPS 30; VPS30
Clonality: Monoclonal
Clone: R02-8D5
Conjugation: Unconjugated
Applications: WB
Field of Research: Cancer; Epigenetics and Nuclear Signaling; Metabolism; Microbiology; Signal Transduction
Purification: Affinity Purified
Concentration: 300 μg/mL
Dilution: WB 1:500-1:1000
Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 52kDa
Observed Molecular Weight: 52kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant Beclin 1 Monoclonal Antibody?

The catalog number for Recombinant Beclin 1 Monoclonal Antibody is E-AB-81447.

What sizes are available for Recombinant Beclin 1 Monoclonal Antibody?

Recombinant Beclin 1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Beclin 1 Monoclonal Antibody come in?

Recombinant Beclin 1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Beclin 1 Monoclonal Antibody in stock?

Recombinant Beclin 1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Beclin 1 Monoclonal Antibody?

Recombinant Beclin 1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Beclin 1 Monoclonal Antibody?

Estimated delivery time for Recombinant Beclin 1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Beclin 1 Monoclonal Antibody?

The safety data sheet for Recombinant Beclin 1 Monoclonal Antibody is available here: https://789.bio/eb/qn1u1O.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.