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Product details

Recombinant Keap1 Monoclonal Antibody

Catalog number E-AB-81505-01

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Price for E-AB-81505-01

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Size / count 50 µL

Specifications

Catalog number
E-AB-81505-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
KEAP1, also named as INRF2, KIAA0132 and KLHL19, is part of a multiprotein complex that contains the CUL3-ROC1 ubiquitin ligase, which can ubiquitinate the N-terminal domain of NRF2. Two molecules of KEAP1 bind to two distinct sites in the N-terminal region of NRF2, the ETGE and DLG sites, which affect the KEAP1-NRF2 interaction and/or its physiological consequences. KEAP1 retains NFE2L2/NRF2 in the cytosol. It functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. It also retains BPTF in the cytosol. This antibody is a mouse monoclonal antibody raised against residues near the C terminus of human KEAP1.
Abbreviation
Keap1
UniProt
Q14145
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human Keap1
Target
Cytosolic inhibitor of Nrf2; INrf 2; INrf2; Keap 1; KEAP1; KEAP1; Kelch like ECH associated protein 1; Kelch like family member 19; Kelch like protein 19; Kelch-like ECH-associated protein 1; Kelch-like protein 19; KIAA0132; KLHL 19; KLHL19; MGC10630; MGC1114; MGC20887; MGC4407; MGC9454
Clonality
Monoclonal
Clone
R02-1H7
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:20-1:50
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
70kDa
Observed Molecular Weight
60/64kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Recombinant Keap1 Monoclonal Antibody?

The catalog number for Recombinant Keap1 Monoclonal Antibody is E-AB-81505.

What sizes are available for Recombinant Keap1 Monoclonal Antibody?

Recombinant Keap1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Keap1 Monoclonal Antibody come in?

Recombinant Keap1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Keap1 Monoclonal Antibody in stock?

Recombinant Keap1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Keap1 Monoclonal Antibody?

Recombinant Keap1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Keap1 Monoclonal Antibody?

Estimated delivery time for Recombinant Keap1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Keap1 Monoclonal Antibody?

The safety data sheet for Recombinant Keap1 Monoclonal Antibody is available here: https://789.bio/eb/WbzTOC.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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