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Product details

Recombinant ASK1 Monoclonal Antibody

Catalog number E-AB-81532-01

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Price for E-AB-81532-01

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Size / count 50 µL

Specifications

Catalog number
E-AB-81532-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK) . MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK) /stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
Abbreviation
ASK1
UniProt
Q99683
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human ASK1
Target
Apoptosis signal regulating kinase 1; Apoptosis signal-regulating kinase 1; ASK 1; ASK-1; ASK1; M3K5; M3K5; MAP/ERK kinase kinase 5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; MEKK5; Mitogen activated protein kinase kinase kinase 5; Mitogen-activated protein kinase kinase kinase 5
Clonality
Monoclonal
Clone
R06-4F5
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Cardiovascular
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
155kDa
Observed Molecular Weight
155kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Recombinant ASK1 Monoclonal Antibody?

The catalog number for Recombinant ASK1 Monoclonal Antibody is E-AB-81532.

What sizes are available for Recombinant ASK1 Monoclonal Antibody?

Recombinant ASK1 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant ASK1 Monoclonal Antibody come in?

Recombinant ASK1 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant ASK1 Monoclonal Antibody in stock?

Recombinant ASK1 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant ASK1 Monoclonal Antibody?

Recombinant ASK1 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant ASK1 Monoclonal Antibody?

Estimated delivery time for Recombinant ASK1 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant ASK1 Monoclonal Antibody?

The safety data sheet for Recombinant ASK1 Monoclonal Antibody is available here: https://789.bio/eb/DGCSmP.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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