Recombinant Axin 2 Monoclonal Antibody

Catalog number E-AB-81534-01

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Price for E-AB-81534-01

Size / count 50 µL

Specifications

Catalog number: E-AB-81534-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
Abbreviation: Axin 2
UniProt: Q9Y2T1
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: A synthetic peptide of human Axin 2
Target: AXIN2; AXIL; ODCRCS; axin-2
Clonality: Monoclonal
Clone: R06-3A8
Conjugation: Unconjugated
Applications: WB
Field of Research: Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Neuroscience; Stem Cells
Purification: Affinity Purified
Concentration: 300 μg/mL
Dilution: WB 1:500-1:1000
Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 94kDa
Observed Molecular Weight: 94kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant Axin 2 Monoclonal Antibody?

The catalog number for Recombinant Axin 2 Monoclonal Antibody is E-AB-81534.

What sizes are available for Recombinant Axin 2 Monoclonal Antibody?

Recombinant Axin 2 Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Axin 2 Monoclonal Antibody come in?

Recombinant Axin 2 Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Axin 2 Monoclonal Antibody in stock?

Recombinant Axin 2 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Axin 2 Monoclonal Antibody?

Recombinant Axin 2 Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Axin 2 Monoclonal Antibody?

Estimated delivery time for Recombinant Axin 2 Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Axin 2 Monoclonal Antibody?

The safety data sheet for Recombinant Axin 2 Monoclonal Antibody is available here: https://789.bio/eb/qD0OeL.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.