Recombinant Bcr Monoclonal Antibody — image 1 of 2

Product details

Recombinant Bcr Monoclonal Antibody

Catalog number E-AB-81535-01

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Price for E-AB-81535-01

Size / count 50 µL

Specifications

Catalog number: E-AB-81535-01
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation: Bcr
UniProt: P11274
Host: Rabbit
Reactivity: Human
Immunogen: A synthetic peptide of human Bcr
Target: ALL; bcr; BCR1; Breakpoint cluster region; CML; D22S11; D22S662; PHL; Renal carcinoma antigen NY-REN-26
Clonality: Monoclonal
Clone: R02-6I0
Conjugation: Unconjugated
Applications: WB; IHC-P
Field of Research: Cancer; Signal Transduction
Purification: Affinity Purified
Concentration: 300 μg/mL
Dilution: WB 1:1000-1:2000; IHC 1:50-1:100
Buffer: 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 143kDa
Observed Molecular Weight: 160kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for Recombinant Bcr Monoclonal Antibody?

The catalog number for Recombinant Bcr Monoclonal Antibody is E-AB-81535.

What sizes are available for Recombinant Bcr Monoclonal Antibody?

Recombinant Bcr Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Bcr Monoclonal Antibody come in?

Recombinant Bcr Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Bcr Monoclonal Antibody in stock?

Recombinant Bcr Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Bcr Monoclonal Antibody?

Recombinant Bcr Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Bcr Monoclonal Antibody?

Estimated delivery time for Recombinant Bcr Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Bcr Monoclonal Antibody?

The safety data sheet for Recombinant Bcr Monoclonal Antibody is available here: https://789.bio/eb/mrDWH8.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.