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Product details

Recombinant Fas Monoclonal Antibody

Catalog number E-AB-81556-01

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Price for E-AB-81556-01

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Size / count 50 µL

Specifications

Catalog number
E-AB-81556-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
FAS, also named as CD95, APO-1, APT1, FAS1 and TNFRSF6, is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily, can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC) . FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro) . This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.
Abbreviation
Fas
UniProt
P25445
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide of human Fas
Target
ALPS 1A; ALPS1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo-1 antigen; APO1; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen FAS; Apoptosis-mediating surface antigen FAS; APT 1; APT1; CD 95; CD 95 antigen; CD95; CD95 antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; Fas (TNF receptor superfamily; member 6) ; FAS 1; FAS 827dupA; Fas AMA; Fas; FAS Antigen; Fas cell surface death receptor; FAS1; FASLG receptor; FASTM; sFAS; Surface antigen APO1; TNF receptor superfamily; member 6; TNFRSF 6; TNFRSF6; TNR6; Tumor necrosis factor receptor superfamily member 6
Clonality
Monoclonal
Clone
R02-8I7
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Cell Biology; Immunology
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38kDa
Observed Molecular Weight
45kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Recombinant Fas Monoclonal Antibody?

The catalog number for Recombinant Fas Monoclonal Antibody is E-AB-81556.

What sizes are available for Recombinant Fas Monoclonal Antibody?

Recombinant Fas Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Fas Monoclonal Antibody come in?

Recombinant Fas Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Fas Monoclonal Antibody in stock?

Recombinant Fas Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Fas Monoclonal Antibody?

Recombinant Fas Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Fas Monoclonal Antibody?

Estimated delivery time for Recombinant Fas Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Fas Monoclonal Antibody?

The safety data sheet for Recombinant Fas Monoclonal Antibody is available here: https://789.bio/eb/Dij1O0.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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