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Product details

Recombinant Lamin A/C Monoclonal Antibody

Catalog number E-AB-81577-01

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Price for E-AB-81577-01

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Size / count 50 µL

Specifications

Catalog number
E-AB-81577-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Abbreviation
Lamin A/C
UniProt
P02545
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
A synthetic peptide of human Lamin A/C
Target
70 kDa lamin; Cardiomyopathy dilated 1A (autosomal dominant) ; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; Lamin A; Lamin A/C; Lamin A/C like 1; Lamin; Lamin C; Lamin-A/C; LDP1; LFP; LGMD1B; Limb girdle muscular dystrophy 1B (autosomal dominant) ; LMN 1; LMN A; LMN C; LMN1; LMNA; LMNA; LMNC; LMNL1; Prelamin A/C; PRO1; Renal carcinoma antigen NY REN 32; Renal carcinoma antigen NY-REN-32; Renal carcinoma antigen NYREN32
Clonality
Monoclonal
Clone
R07-1I5
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cancer; Signal Transduction; Tags and Cell Markers
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:1000-1:2000; IHC 1:50-1:100
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
74 kDa
Observed Molecular Weight
74/63 kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Recombinant Lamin A/C Monoclonal Antibody?

The catalog number for Recombinant Lamin A/C Monoclonal Antibody is E-AB-81577.

What sizes are available for Recombinant Lamin A/C Monoclonal Antibody?

Recombinant Lamin A/C Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant Lamin A/C Monoclonal Antibody come in?

Recombinant Lamin A/C Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant Lamin A/C Monoclonal Antibody in stock?

Recombinant Lamin A/C Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant Lamin A/C Monoclonal Antibody?

Recombinant Lamin A/C Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant Lamin A/C Monoclonal Antibody?

Estimated delivery time for Recombinant Lamin A/C Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant Lamin A/C Monoclonal Antibody?

The safety data sheet for Recombinant Lamin A/C Monoclonal Antibody is available here: https://789.bio/eb/90Ce5S.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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