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Product details

Recombinant LC3A Monoclonal Antibody

Catalog number E-AB-81578-01

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Price for E-AB-81578-01

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Size / count 50 µL

Specifications

Catalog number
E-AB-81578-01
Size / count
50 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
LC3, also known as microtubule-associated protein 1 light chain 3 (MAP1LC3), is a mammalian homolog of the yeast Atg8p (autophagy-related 8 protein) that is involved in autophagy process. Three isoforms of LC3 exist as LC3A, LC3B, and LC3C. LC3 is first synthesized as pro-LC3, and undergoes C-terminal cleavage to yield a cytosolic precursor known as LC3-I. During autophagy LC3-I is subsequently conjugated to PE lipid as lipidated form: LC3-II. The lipidated form migrates faster on SDS-PAGE gel. The increased the level of LC3-II has been widely used as autophagy marker. This antibody recognizes both LC3-I and LC3-II.
Abbreviation
LC3A
UniProt
Q9H492
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human MAP1LC3A
Target
ATG8E; Autophagy-related protein LC3 A; Autophagy-related ubiquitin-like modifier LC3 A; LC3; LC3A; MAP1 light chain 3 like protein 1; MAP1 light chain 3-like protein 1; MAP1A/1B light chain 3 A; MAP1A/MAP1B LC3 A; MAP1A/MAP1B light chain 3 A; MAP1ALC3; MAP1BLC3; Map1lc3a; Microtubule associated proteins 1A/1B light chain 3; Microtubule-associated protein 1 light chain 3 alpha; Microtubule-associated proteins 1A and 1B; light chain 3; Microtubule-associated proteins 1A/1B light chain 3A; MLP3A
Clonality
Monoclonal
Clone
R05-1B6
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction
Purification
Affinity Purified
Concentration
300 μg/mL
Dilution
WB 1:500-1:1000
Buffer
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
14kDa
Observed Molecular Weight
16kDa
Citation 01
https://www.frontiersin.org/articles/10.3389/fonc.2019.01469/full
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Recombinant LC3A Monoclonal Antibody?

The catalog number for Recombinant LC3A Monoclonal Antibody is E-AB-81578.

What sizes are available for Recombinant LC3A Monoclonal Antibody?

Recombinant LC3A Monoclonal Antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does Recombinant LC3A Monoclonal Antibody come in?

Recombinant LC3A Monoclonal Antibody is available in 2 different pack sizes.

Is Recombinant LC3A Monoclonal Antibody in stock?

Recombinant LC3A Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Recombinant LC3A Monoclonal Antibody?

Recombinant LC3A Monoclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Recombinant LC3A Monoclonal Antibody?

Estimated delivery time for Recombinant LC3A Monoclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Recombinant LC3A Monoclonal Antibody?

The safety data sheet for Recombinant LC3A Monoclonal Antibody is available here: https://789.bio/eb/LW5CCK.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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