Recombinant Prohibitin Monoclonal Antibody

Specifications

Catalog number

E-AB-81601-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .

Abbreviation

Prohibitin

UniProt

P35232

Host

Rabbit

Reactivity

Human; Rat

Immunogen

A synthetic peptide of human Prohibitin

Target

Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB; PHB1; Prohibitin

Clonality

Monoclonal

Clone

R07-2G1

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Tags and Cell Markers

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:500-1:1000; IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

30 kDa

Observed Molecular Weight

30 kDa

Isotype

IgG