Recombinant Tissue Factor Monoclonal Antibody

Specifications

Catalog number

E-AB-81613-01

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Abbreviation

Tissue Factor

UniProt

P13726

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

A synthetic peptide of human Tissue Factor

Target

CD142; CD142 antigen; Coagulation factor III (thromboplastin tissue factor) ; Coagulation factor III; F3; FLJ17960; TF; TF; TFA; Thromboplastin; Tissue factor

Clonality

Monoclonal

Clone

R04-7G2

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cancer; Cardiovascular

Purification

Affinity Purified

Concentration

300 μg/mL

Dilution

WB 1:1000-1:2000; IHC 1:50-1:100

Buffer

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

33kDa

Observed Molecular Weight

45kDa

Isotype

IgG