CDK12 Polyclonal Antibody — image 1 of 4

Product details

CDK12 Polyclonal Antibody

Catalog number E-AB-90992-01

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Price for E-AB-90992-01

Size / count 60 µL

Specifications

Catalog number: E-AB-90992-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD of the large subunit of RNA polymerase II (POLR2A, thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates 'Ser-5' in CTD repeats that are already phosphorylated at 'Ser-7', but can also phosphorylate 'Ser-2'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.
Abbreviation: CDK12
UniProt: Q9NYV4
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant fusion protein of human CDK12
Target: CDK12; CRK7; CRKR; CRKRS
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Signal Transduction
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IHC 1:50-1:200
Buffer: PBS with 0.05% proclin300,50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 141kDa/163kDa/164kDa
Observed Molecular Weight: 205KDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CDK12 Polyclonal Antibody?

The catalog number for CDK12 Polyclonal Antibody is E-AB-90992.

What sizes are available for CDK12 Polyclonal Antibody?

CDK12 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does CDK12 Polyclonal Antibody come in?

CDK12 Polyclonal Antibody is available in 3 different pack sizes.

Is CDK12 Polyclonal Antibody in stock?

CDK12 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CDK12 Polyclonal Antibody?

CDK12 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CDK12 Polyclonal Antibody?

Estimated delivery time for CDK12 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CDK12 Polyclonal Antibody?

The safety data sheet for CDK12 Polyclonal Antibody is available here: https://789.bio/eb/vrfHGS.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.