Alkaline Phosphatase (ALPL) Polyclonal Antibody

Specifications

Catalog number

E-AB-93077-01

Size / count

60 µL

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.

Abbreviation

Alkaline Phosphatase (ALPL)

UniProt

P05186

Host

Rabbit

Reactivity

Human; Mouse; Rat

Immunogen

Recombinant fusion protein of human Alkaline Phosphatase

Target

ALPL; AP-TNAP; APTNAP; HOPS; TNAP

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Cell Biology; Tags and Cell Markers

Purification

Affinity purification

Concentration

1mg/mL

Dilution

WB 1:500-1:2000; IHC 1:50-1:200

Buffer

PBS with 0.01% thiomersal,50% glycerol, pH7.3.

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

48kDa/51kDa/57kDa

Observed Molecular Weight

80KDa

Isotype

IgG