NLRP3 Polyclonal Antibody — image 1 of 3

Product details

NLRP3 Polyclonal Antibody

Catalog number E-AB-93112-01

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Price for E-AB-93112-01

Size / count 60 µL

Specifications

Catalog number: E-AB-93112-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID) . Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
Abbreviation: NLRP3
UniProt: Q96P20
Host: Rabbit
Reactivity: Human; Mouse; Rat
Immunogen: Recombinant fusion protein of human NLRP3
Target: NLRP3; AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; FCAS; FCAS1; FCU; MWS; NALP3; PYPAF1
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Cancer; Cell Biology; Cardiovascular; Immunology; Signal Transduction
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:200-1:1000; IF 1:20-1:200
Buffer: PBS with 0.05% proclin300,50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 83kDa/105kDa/111kDa/112kDa/115kDa/118kDa
Observed Molecular Weight: 110KDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for NLRP3 Polyclonal Antibody?

The catalog number for NLRP3 Polyclonal Antibody is E-AB-93112.

What sizes are available for NLRP3 Polyclonal Antibody?

NLRP3 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does NLRP3 Polyclonal Antibody come in?

NLRP3 Polyclonal Antibody is available in 3 different pack sizes.

Is NLRP3 Polyclonal Antibody in stock?

NLRP3 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NLRP3 Polyclonal Antibody?

NLRP3 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for NLRP3 Polyclonal Antibody?

Estimated delivery time for NLRP3 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NLRP3 Polyclonal Antibody?

The safety data sheet for NLRP3 Polyclonal Antibody is available here: https://789.bio/eb/eXH0eH.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.