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Product details

Caspase-1 Polyclonal Antibody

Catalog number E-AB-93169-01

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Price for E-AB-93169-01

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Size / count 60 μL

Specifications

Catalog number
E-AB-93169-01
Size / count
60 μL
Dry ice
No
Hazardous
No
Discontinued
No
Background
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.
Abbreviation
Caspase-1
UniProt
P29466
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant fusion protein of human Caspase-1
Target
CASP1; ICE; IL1BC; P45; caspase-1; Caspase 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cell Biology; Metabolism
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
10kDa/29kDa/35kDa/42kDa/45kDa
Observed Molecular Weight
48KDa/20-25KDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for Caspase-1 Polyclonal Antibody?

The catalog number for Caspase-1 Polyclonal Antibody is E-AB-93169.

What sizes are available for Caspase-1 Polyclonal Antibody?

Caspase-1 Polyclonal Antibody is available in the following size(s): 60 μL, 120 μL, 200 µL.

How many pack sizes does Caspase-1 Polyclonal Antibody come in?

Caspase-1 Polyclonal Antibody is available in 3 different pack sizes.

Is Caspase-1 Polyclonal Antibody in stock?

Caspase-1 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caspase-1 Polyclonal Antibody?

Caspase-1 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for Caspase-1 Polyclonal Antibody?

Estimated delivery time for Caspase-1 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caspase-1 Polyclonal Antibody?

The safety data sheet for Caspase-1 Polyclonal Antibody is available here: https://789.bio/eb/jjbXHC.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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