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Product details

IL18 Polyclonal Antibody

Catalog number E-AB-93262-01

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Price for E-AB-93262-01

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Size / count 60 µL

Specifications

Catalog number
E-AB-93262-01
Size / count
60 µL
Dry ice
No
Hazardous
No
Discontinued
No
Background
Interleukin-18 (L-18) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS) . After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Abbreviation
IL18
UniProt
P70380
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant fusion protein of mouse IL18
Target
Ig; Il-; Igif; Il-18
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
22kDa
Observed Molecular Weight
22kDa/18kDa
Isotype
IgG

Frequently Asked Questions

What is the catalog number for IL18 Polyclonal Antibody?

The catalog number for IL18 Polyclonal Antibody is E-AB-93262.

What sizes are available for IL18 Polyclonal Antibody?

IL18 Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does IL18 Polyclonal Antibody come in?

IL18 Polyclonal Antibody is available in 3 different pack sizes.

Is IL18 Polyclonal Antibody in stock?

IL18 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IL18 Polyclonal Antibody?

IL18 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for IL18 Polyclonal Antibody?

Estimated delivery time for IL18 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IL18 Polyclonal Antibody?

The safety data sheet for IL18 Polyclonal Antibody is available here: https://789.bio/eb/1uHefD.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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