Product details

VEGF Polyclonal Antibody

Catalog number E-AB-93319-01

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Price for E-AB-93319-01

Size / count 60 µL

Specifications

Catalog number: E-AB-93319-01
Size / count: 60 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.
Abbreviation: VEGF
UniProt: P15692
Host: Rabbit
Reactivity: Human; Mouse
Immunogen: A synthetic peptide of human VEGF
Target: VEGFA; MVCD1; VEGF; VPF; vascular endothelial growth factor A
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IF
Field of Research: Cancer; Cardiovascular; Metabolism; Developmental Biology; Signal Transduction
Purification: Affinity purification
Concentration: 1mg/mL
Dilution: WB 1:500-1:2000; IF 1:50-1:200
Buffer: PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 15-27kDa/34-45kDa
Observed Molecular Weight: 17KDa/45KDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for VEGF Polyclonal Antibody?

The catalog number for VEGF Polyclonal Antibody is E-AB-93319.

What sizes are available for VEGF Polyclonal Antibody?

VEGF Polyclonal Antibody is available in the following size(s): 60 µL, 120 µL, 200 µL.

How many pack sizes does VEGF Polyclonal Antibody come in?

VEGF Polyclonal Antibody is available in 3 different pack sizes.

Is VEGF Polyclonal Antibody in stock?

VEGF Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures VEGF Polyclonal Antibody?

VEGF Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for VEGF Polyclonal Antibody?

Estimated delivery time for VEGF Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for VEGF Polyclonal Antibody?

The safety data sheet for VEGF Polyclonal Antibody is available here: https://789.bio/eb/jzTef9.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.