AF/LE Purified Anti-Human CD16 Antibody[3G8]

Specifications

Catalog number

E-AB-F12360-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Abbreviation

CD16

Gene ID

2214;2215

UniProt

P08637; O75015

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD16 protein

Target

FCR; IMD; FCG; Fcgr; IGFR; IgG Fc Receptor III; CD16; CD16A; FCG3; FCGR3; FCGRIII; FCR-10; FCRIII; FCRIIIA; IGFR3; IMD20; FCGR3A; CD16a Antigen; Fc-Gamma RIII; Fc-gamma RIIIa; Fc-Gamma RIII-Alpha; IgG Fc Receptor III-2; Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A; Fc&gamma-RIIIA-A; CD16a; CD 16; CD 16a; CD16B; CD16b antigen; Fc fragment of IgG; Fc fragment of IgG low affinity IIIa receptor; Fc fragment of IgG low affinity IIIa receptor (CD16) ; Fc fragment of IgG receptor IIIa; Fc gamma R3; Fc gamma receptor III 2 (CD 16) ; Fc gamma receptor III A; Fc gamma receptor IIIA; Fc gamma receptor IIIb (CD 16) ; Fc gamma RIII; Fc gamma RIII alpha; Fc gamma RIII beta; Fc gamma RIIIa; Fc gamma RIIIb; Fc of IgG; FCG 3; FCG3A; Fc-gamma receptor III2 (CD 16) ; Fc-gamma receptor III2 (CD16) ; Fc-gamma receptor IIIb (CD16) ; FCgammaRIIIA; FCGR 3; FCGR 3A; FCGR3A protein; FCGRIII-2; FcR 10; FcR10; IGFR 3; IgG Fc receptor III 1; IgG Fc receptor III 2; immunoglobulin G Fc receptor III; immunoglobulin G Fc receptor III-2; low affinity III; low affinity IIIa; Low affinity IIIa receptor; low affinity IIIb; Low affinity immunoglobulin gamma Fc region receptor III A; Low affinity immunoglobulin gamma Fc region receptor IIIB; neutrophil-specific antigen NA; receptor (CD16) ; receptor (CD16a) ; receptor (CD16b) ; receptor for; receptor for (CD16) ; FCG; FCR; Fcgr; IgG Fc receptor III; IGFR; FCGR3B; CD16; CD16b; FCG3; FCGR3; FCR-10; FCRIII; FCRIIIb; CD16b and FCGR3B; CD16b and FCGR4B; CD16b and FCGR5B; CD16b and FCGR6B; Fc-gamma RIII-beta; IgG Fc receptor III-1; Low affinity immunoglobulin gamma Fc region receptor III-B; IGFR3; Fc&gamma-RIIIB-B; CD16A; Fc fragment of IgG receptor IIIb; FCGR3A

Clonality

Monoclonal

Clone

3G8

Conjugation

None (AF/LE)

Applications

FCM; Block

Field of Research

Immunology; Stem Cells; Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Citation 01

https://www.sciencedirect.com/science/article/pii/S096999612500049X

Isotype

Mouse IgG1, κ