Recombinant Human IL-2 protein (His tag)

Specifications

Catalog number

PDMH100130-01

Size / count

20 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system, belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

Abbreviation

IL-2

Synonyms

IL2; IL-2; TCGF; lymphokine; IL3; IL4; IL5; IL6; Aldesleukin; IL-2lymphokine; interleukin-2; Proleukin; interleukin 2; involved in regulation of T-cell clonal expansion; T cell growth factor; T-cell growth factor; IL 2; IL2; Interleukin 2; interleukin2; Involved in regulation of T cell clonal expansion; Lymphokine; POIL2; T Cell Growth Factor; TCGF

UniProt

P60568

Accession Number

P60568

Expression System

HEK293 Cells

Tag

C-His

Sequence

Met1-Thr153

Field of Research

Immunology; cytokine

Endotoxin

< 1.0 EU/mg of the protein as determined by the LAL method.

Purity

> 95% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

16.7 kDa

Observed Molecular Weight

17 kDa

Species

Human