Recombinant Mouse Podoplanin/PDPN Protein (His Tag)

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Catalog number PDMM100018-01

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Price for PDMM100018-01

Size / count 20 µg

Specifications

Catalog number: PDMM100018-01
Size / count: 20 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Podoplanin, also known as&nbsp, PDPN, is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined. Alternatively spliced transcript variants encoding different isoforms have been identified.PDPN is a mucin-type glycoprotein negatively charged by extensive O-glycosylation and a high content of sialic acid, which expresses the adhesive property. It is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. PDPN may contribute to form odontoblastic fiber or function as the anchorage to the tooth development and in proliferating epithelial cells of cervical loop and apical bud. The intensity of podoplanin expression is negatively correlated with the expression of CD34 and factor VIII. Podoplanin would be useful as a diagnostic marker for epithelioid hemangioendothelioma in liver tumors.
Abbreviation: Podoplanin; PDPN
Synonyms: Aggrus; Glycoprotein 38; Gp38; OTS-8; PA2.26 antigen; Podoplanin; RANDAM-2; T1-alpha; T1a; T1alpha
UniProt: Q62011
Accession Number: Q62011
Expression System: HEK293 Cells
Tag: C-His
Sequence: Met 1-Leu 141
Endotoxin: < 1.0 EU/mg of the protein as determined by the LAL method.
Purity: > 95% as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight: 15.4 kDa
Observed Molecular Weight: 20-30 kDa
Species: Mouse

Product documents

Supporting information for this product.

Product Datasheet

Frequently Asked Questions

How do I request a quotation for this product?

Add the product and required quantity to your cart, then submit the quotation request from the checkout page. Include your contact and delivery details so the Afraxis team can respond.

How can I identify the product or variant I need?

Check the product description, specifications and catalogue number on this page. If the product has multiple variants, select the required catalogue number and size before adding it to your cart.

Where can I find product documentation?

Available product documents are listed in the Product documents section on this page. If a document you need is not listed, contact Afraxis and include the product name and catalogue number.

How do I check the price and availability?

The product page shows the available variant and any displayed price information. For a quotation or confirmation for your order, add the product to your cart and submit a request.

How long will delivery take?

Delivery timing depends on the product, supplier and destination. Request a quotation with your delivery details to confirm the expected timing for your order.

Does this product require special handling or shipping?

Review any product-specific handling details shown on this page. If you are unsure about storage or shipping requirements, contact Afraxis with the product name and catalogue number.

Who can use Afraxis products?

Afraxis products are supplied for laboratory and research use. Review the product documentation and intended-use information before use.

How do I contact Afraxis about this product?

Use the contact form or contact details on the Afraxis website. Include the product name and catalogue number so the team can assist with your enquiry.