Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (His&GST Tag) — image 1 of 3

Product details

Recombinant Human SPHK1/Sphingosine Kinase 1 Protein (His&GST Tag)

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Catalog number PKSH030316

Price for PKSH030316

Size / count 50 µg

Specifications

Catalog number: PKSH030316
Size / count: 50 µg
Dry ice: No
Hazardous: No
Discontinued: No
Background: SPHK1; also known as sphingosine Kinase 1; catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P) . S1P exhibits a broad spectrum of biological activities including cell proliferation; survival; migration; cytoskeletal organization; and morphogenesis. It is a ligand for cell surface G protein-coupled receptors. SPHK 1 is a potential therapeutic target for the control of cancer and inflammation. SPHK1 plays a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory; antiapoptotic; and immune processes.
Synonyms: SPHK; SPHK1; SPK
UniProt: Q9NYA1
Accession Number: Q9NYA1-1
Expression System: Baculovirus-Insect Cells
Tag: N-His-GST
Sequence: Met 1-Leu 384
Field of Research: Signal Transduction, Cancer, Metabolism
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Purity: > 95 % as determined by reducing SDS-PAGE.
Bioactivity: Not validated for activity
Reconstitution: Not Applicable
Shipping Conditions: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight: 70.3 kDa
Observed Molecular Weight: 64 kDa
Formulation: Supplied as sterile solution of 20mM Tris, 500mM NaCl, 3mM DTT, 10% glycerol, pH 8.0
Species: Human

Product documents

Supporting information for this product.

Product Datasheet

Frequently Asked Questions

How do I request a quotation for this product?

Add the product and required quantity to your cart, then submit the quotation request from the checkout page. Include your contact and delivery details so the Afraxis team can respond.

How can I identify the product or variant I need?

Check the product description, specifications and catalogue number on this page. If the product has multiple variants, select the required catalogue number and size before adding it to your cart.

Where can I find product documentation?

Available product documents are listed in the Product documents section on this page. If a document you need is not listed, contact Afraxis and include the product name and catalogue number.

How do I check the price and availability?

The product page shows the available variant and any displayed price information. For a quotation or confirmation for your order, add the product to your cart and submit a request.

How long will delivery take?

Delivery timing depends on the product, supplier and destination. Request a quotation with your delivery details to confirm the expected timing for your order.

Does this product require special handling or shipping?

Review any product-specific handling details shown on this page. If you are unsure about storage or shipping requirements, contact Afraxis with the product name and catalogue number.

Who can use Afraxis products?

Afraxis products are supplied for laboratory and research use. Review the product documentation and intended-use information before use.

How do I contact Afraxis about this product?

Use the contact form or contact details on the Afraxis website. Include the product name and catalogue number so the team can assist with your enquiry.

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